News — histamine intolerance

For those struggling with chronic migraines, unpredictable digestive distress, or mysterious flushing, the culprit may not be an allergy, but a simple enzyme deficiency. This is the **DAO-Histamine Pathway**—a critical balance between the histamine we consume (and produce) and the **Diamine Oxidase (DAO)** enzyme our small intestine creates to break it down.

When DAO levels drop due to genetics, gut damage, or certain medications, dietary histamine floods the bloodstream, contributing to neuroinflammation, vascular headaches, and systemic sensitivity. This article dives deep into the science of histamine intolerance, its central role in the gut-brain axis, and practical strategies—from dietary changes to targeted supplementation—to restore this essential balance and find relief.

For those battling unexplained headaches, skin rashes, digestive troubles, or anxiety, the culprit might not be the usual suspects—gluten, dairy, or sugar—but something far less known: histamine intolerance. While histamine plays a critical role in your immune system, when your body struggles to break it down effectively, it can trigger a cascade of frustrating symptoms. That’s where the low-histamine diet comes in, offering a powerful and natural route to relief.

Understanding histamine intolerance is the first step toward reclaiming your vitality. With symptoms that mimic everything from allergies to chronic fatigue, it’s no wonder many people go undiagnosed or misdiagnosed for years. This guide walks you through the low-histamine lifestyle—from the science behind histamines to a step-by-step approach for reducing them in your diet. Whether you're newly diagnosed or just exploring potential causes of persistent health issues, this guide will equip you with practical tools and insight for symptom management and long-term relief.